Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MLYCD | O95822 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471455 | 0.98 | HPGD (0.68) | HPGDALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL27479149 | 0.84 | HPGD (1.00) | HPGDALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL7132525 | 0.84 | HPGD (1.00) | HPGDALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL19611154 | 0.84 | HPGD (0.66) | HPGDALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL17560151 | 0.83 | PHGDH (0.63) | HPGDALDH1A1KMT2ATSHRHTT | |
| SCHEMBL10721733 | 0.82 | HPGD (0.95) | HPGDALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL23349085 | 0.82 | HPGD (0.71) | HPGDALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL22106122 | 0.82 | HPGD (0.71) | HPGDALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL14508007 | 0.81 | HPGD (0.61) | HPGDALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL939012 | 0.81 | HPGD (0.53) | HPGDALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162152-A | Monofilaments | HOECHST CELANESE CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0499427-A2 | Poly(2-methyl-1,5-pentylene) terephthalamide : a method of using; a method of spinning; and a process for making | HOECHST CELANESE CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| US-5112685-A | Papermaking | HOECHST CELANESE CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |