Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 2/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685144 | 1.00 | THRA (0.45) | THRATHRBNR5A1TSHRALDH1A1 | |
| SCHEMBL9683858 | 1.00 | THRA (0.45) | THRATHRBNR5A1TSHRALDH1A1 | |
| SCHEMBL9684013 | 1.00 | THRA (0.45) | THRATHRBNR5A1TSHRALDH1A1 | |
| SCHEMBL9683839 | 1.00 | THRA (0.45) | THRATHRBNR5A1TSHRALDH1A1 | |
| SCHEMBL9683865 | 0.98 | THRA (0.43) | THRATHRBNR5A1TSHRALDH1A1 | |
| SCHEMBL9683985 | 0.91 | NPC1 (0.44) | THRATHRBNR5A1TSHRTLR4 | |
| SCHEMBL8405077 | 0.86 | NPC1 (0.44) | THRATHRBNR5A1TSHRTLR4 | |
| SCHEMBL1259530 | 0.85 | NR5A1 (0.44) | THRATHRBNR5A1LPAR2S1PR2 | |
| SCHEMBL10693533 | 0.83 | NR5A1 (0.52) | THRATHRBNR5A1TSHRLPAR2 | |
| SCHEMBL10858978 | 0.83 | NR5A1 (0.52) | THRATHRBNR5A1TSHRLPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106522-A | Liquid hydrophobic vehicle for electro-rheological fluid | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-04-21 | — | — | US | claimed |
| EP-0150994-B1 | ELECTRO-RHEOLOGICAL FLUID COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-11-19 | — | — | EP | claimed |
| EP-0150994-A1 | Electro-rheological fluid compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-08-07 | — | — | EP | claimed |
| US-5106522-A | Liquid hydrophobic vehicle for electro-rheological fluid | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-04-21 | — | — | US | disclosed |
| EP-0150994-B1 | ELECTRO-RHEOLOGICAL FLUID COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-11-19 | — | — | EP | disclosed |
| EP-0150994-A1 | Electro-rheological fluid compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-08-07 | — | — | EP | disclosed |