Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685134 | 1.00 | THRA (0.45) | THRATHRBSMPD1PTPN11S1PR3 | |
| SCHEMBL9684798 | 1.00 | THRA (0.45) | THRATHRBSMPD1PTPN11S1PR3 | |
| SCHEMBL8109088 | 0.98 | THRA (0.43) | THRATHRBSMPD1PTPN11S1PR3 | |
| SCHEMBL9685182 | 0.92 | CYP1A2 (0.44) | THRATHRBNR5A1MEN1LMNA | |
| SCHEMBL11406541 | 0.88 | F2 (0.39) | MEN1LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL11398711 | 0.86 | HPGD (0.44) | MEN1LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL9751184 | 0.86 | MEN1 (0.39) | THRATHRBMEN1CYP3A4MAPT | |
| SCHEMBL9751191 | 0.86 | MEN1 (0.39) | THRATHRBMEN1CYP3A4MAPT | |
| SCHEMBL9751169 | 0.86 | MEN1 (0.39) | THRATHRBMEN1CYP3A4MAPT | |
| SCHEMBL15391585 | 0.86 | THRA (0.44) | THRATHRBSMPD1PTPN11S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106522-A | Liquid hydrophobic vehicle for electro-rheological fluid | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-04-21 | — | — | US | claimed |
| EP-0150994-B1 | ELECTRO-RHEOLOGICAL FLUID COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-11-19 | — | — | EP | claimed |
| EP-0150994-A1 | Electro-rheological fluid compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-08-07 | — | — | EP | claimed |
| US-5106522-A | Liquid hydrophobic vehicle for electro-rheological fluid | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-04-21 | — | — | US | disclosed |
| EP-0150994-B1 | ELECTRO-RHEOLOGICAL FLUID COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-11-19 | — | — | EP | disclosed |
| EP-0150994-A1 | Electro-rheological fluid compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-08-07 | — | — | EP | disclosed |