Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP12 | P39900 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146236 | 0.88 | THRB (0.46) | CA1CA2ALOX5ALDH1A1THRB | |
| SCHEMBL29603148 | 0.88 | THRB (0.46) | CA1CA2ALOX5ALDH1A1THRB | |
| SCHEMBL148297 | 0.82 | MAOB (0.47) | CA1CA2P2RX4ALDH1A1MMP2 | |
| SCHEMBL296203 | 0.79 | CA1 (0.49) | CA1CA2THRBMAOBNPC1 | |
| SCHEMBL3409621 | 0.79 | MAOB (0.50) | ALDH1A1THRBMAOBNPC1RAB9A | |
| SCHEMBL27695944 | 0.79 | TSHR (0.49) | CA1CA2ALOX5ALDH1A1THRB | |
| P-Xylene SCHEMBL11360520 | 0.78 | THRB (0.57) | CA1CA2ALDH1A1THRBMEN1 | |
| SCHEMBL31425225 | 0.77 | THRB (0.44) | CA1CA2ALOX5ALDH1A1THRB | |
| SCHEMBL15019921 | 0.77 | THRB (0.44) | CA1CA2ALOX5ALDH1A1THRB | |
| Bicarbonate SCHEMBL29173094 | 0.77 | MAOB (0.48) | ALDH1A1THRBMAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485197-A1 | Polymers and their use for ophthalmic lenses | NESTLE S.A. (CH) | 1992-05-13 | — | — | EP | disclosed |