SCHEMBL9683184

SCHEMBL9683184

C=CCOC(=O)c1cc(N)c(Cl)c(N)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
HSD17B10 Q99714 3/20 0.51
TSHR P16473 2/20 0.51
CYP3A4 P08684 1/20 0.46
SNCA P37840 1/20 0.43
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 2/20 0.37
HPGD P15428 2/20 0.37
TP53 P04637 1/20 0.37
NPC1 O15118 1/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
RHOA P61586 1/20 0.35
MAPT P10636 2/20 0.35
GAA P10253 1/20 0.35
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5102380 0.83 KDM4E (0.54) ALDH1A1HSD17B10TSHRCYP3A4SNCA
SCHEMBL8786993 0.82 HSD17B10 (0.44) ALDH1A1HSD17B10TSHRCYP3A4SNCA
SCHEMBL11162218 0.82 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRCYP3A4SNCA
SCHEMBL254063 0.82 CYP3A4 (0.59) ALDH1A1HSD17B10TSHRCYP3A4SNCA
SCHEMBL5095083 0.81 ALDH1A1 (0.51) ALDH1A1HSD17B10TSHRCYP3A4SNCA
SCHEMBL5557935 0.81 ALDH1A1 (0.51) ALDH1A1HSD17B10TSHRCYP3A4SNCA
SCHEMBL7781811 0.80 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRCYP3A4SNCA
SCHEMBL7185382 0.78 SNCA (0.48) ALDH1A1HSD17B10TSHRCYP3A4SNCA
SCHEMBL11583076 0.78 ESR1 (0.55) ALDH1A1HSD17B10TSHRCYP3A4SNCA
SCHEMBL8788349 0.78 ALDH1A1 (0.65) ALDH1A1HSD17B10TSHRCYP3A4SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5081212-A Having at least on c6-c26 alkyl side chain per repeating group HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-14 US disclosed
US-4663415-A STORAGE STABILITY BAYER AKTIENGESELLSCHAFT (DE) 1987-05-05 US disclosed