Styrene

Styrene

SCHEMBL9683200

C=Cc1ccccc1.O=C1C=CC(=O)N1c1ccc(O)cc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.65
HSP90AA1 P07900 4/20 0.65
PKM P14618 2/20 0.65
MAPK1 P28482 1/20 0.65
NPSR1 Q6W5P4 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
FAAH O00519 6/20 0.51
DDAH1 O94760 1/20 0.46
ALDH1A1 P00352 2/20 0.45
TSHR P16473 1/20 0.45
ME2 P23368 1/20 0.40
ME1 P48163 1/20 0.40
ME3 Q16798 1/20 0.40
HTT P42858 1/20 0.40
ATM Q13315 1/20 0.40
NR1H3 Q13133 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1392538 0.88 MGLL (0.69) MGLLHSP90AA1PKMMAPK1NPSR1
SCHEMBL28074222 0.84 MGLL (0.69) MGLLHSP90AA1PKMMAPK1NPSR1
Phenol SCHEMBL6695797 0.84 MGLL (0.83) MGLLHSP90AA1PKMMAPK1NPSR1
Styrene SCHEMBL11315127 0.84 MGLL (0.65) MGLLHSP90AA1PKMMAPK1NPSR1
Styrene SCHEMBL27990543 0.83 MGLL (0.62) MGLLHSP90AA1PKMFAAHDDAH1
Styrene SCHEMBL15153834 0.83 MGLL (0.56) MGLLHSP90AA1PKMMAPK1NPSR1
Styrene SCHEMBL14862619 0.83 MGLL (0.56) MGLLHSP90AA1PKMMAPK1NPSR1
SCHEMBL1258213 0.82 MGLL (0.65) MGLLHSP90AA1PKMMAPK1NPSR1
Styrene SCHEMBL1070534 0.81 MGLL (0.58) MGLLHSP90AA1PKMMAPK1NPSR1
SCHEMBL140288 0.80 MGLL (1.00) MGLLHSP90AA1PKMMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113122227-A Composite material, preparation method thereof, light-emitting film and display device TCL集团股份有限公司 2021-07-16 CN claimed
CN-113122227-A Composite material, preparation method thereof, light-emitting film and display device TCL集团股份有限公司 2021-07-16 CN disclosed
EP-0474927-A1 Dynamically vulcanized alloys adherent to styrene copolymers and polyester compositions ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1992-03-18 EP disclosed
US-4623578-A Epoxy crosslinked copolymers of polyanhydrides and laminates therefrom WESTINGHOUSE ELECTRIC CORP. (US) 1986-11-18 US disclosed