Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.64 |
| ▸ | DPP4 | P27487 | 5/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684240 | 1.00 | MEN1 (0.76) | MEN1ALDH1A1KMT2AADRB2ADRB3 | |
| SCHEMBL9683310 | 1.00 | MEN1 (0.76) | MEN1ALDH1A1KMT2AADRB2ADRB3 | |
| SCHEMBL9685457 | 1.00 | MEN1 (0.76) | MEN1ALDH1A1KMT2AADRB2ADRB3 | |
| SCHEMBL9684112 | 1.00 | MEN1 (0.76) | MEN1ALDH1A1KMT2AADRB2ADRB3 | |
| SCHEMBL9684119 | 1.00 | MEN1 (0.76) | MEN1ALDH1A1KMT2AADRB2ADRB3 | |
| Hydrochloric Acid SCHEMBL9684970 | 0.99 | MEN1 (0.74) | MEN1ALDH1A1KMT2AADRB2ADRB3 | |
| Hydrochloric Acid SCHEMBL9684962 | 0.99 | MEN1 (0.74) | MEN1ALDH1A1KMT2AADRB2ADRB3 | |
| Hydrochloric Acid SCHEMBL11025068 | 0.89 | ALDH1A1 (0.64) | MEN1ALDH1A1KMT2AADRB2ADRB3 | |
| Hydrochloric Acid SCHEMBL11025071 | 0.89 | ALDH1A1 (0.64) | MEN1ALDH1A1KMT2AADRB2ADRB3 | |
| SCHEMBL9684245 | 0.89 | MEN1 (0.58) | MEN1ALDH1A1KMT2AADRB2ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0140243-B1 | PHENOXYPROPANOL AMINES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-11-09 | — | — | EP | claimed |
| EP-0140243-A2 | Phenoxypropanol amines | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-05-08 | — | — | EP | claimed |
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |
| US-4871755-A | Method for treating diabetes obesity and conditions characterized by increased protein breakdown with novel oxazolidines | HOFFMANN-LA ROCHE INC. (US) | 1989-10-03 | — | — | US | disclosed |
| US-4743604-A | ANTIBESITY, ANTIDIABETIC, FEEDS | HOFFMANN-LA ROCHE INC. (US) | 1988-05-10 | — | — | US | disclosed |
| EP-0140243-A2 | Phenoxypropanol amines | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-05-08 | — | — | EP | disclosed |