Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684667 | 0.79 | POLB (0.48) | POLBKDM5AMAOAMAOBPDE9A | |
| SCHEMBL9684081 | 0.70 | POLB (0.48) | POLBMAOAMAOBPDE9AHPGD | |
| SCHEMBL9684562 | 0.69 | POLB (0.43) | POLBKDM5AMAOAMAOBPDE9A | |
| SCHEMBL21529737 | 0.69 | POLB (0.47) | POLBMAOAMAOBPDE9AHPGD | |
| SCHEMBL9042245 | 0.68 | PDE9A (0.46) | POLBPDE9AHPGDKDM4ENPSR1 | |
| SCHEMBL15996359 | 0.66 | POLB (0.50) | POLBMAOAMAOBPDE9AHPGD | |
| SCHEMBL9226645 | 0.65 | DYRK1A (0.50) | MAOAMAOBPDE9AHPGDKDM4E | |
| SCHEMBL10590025 | 0.65 | KMT2A (0.40) | POLBKDM4EALDH1A1GLAGAA | |
| SCHEMBL9226633 | 0.65 | DYRK1A (0.39) | POLBHPGDKDM4ENPSR1PPARG | |
| SCHEMBL9518605 | 0.65 | DYRK1A (0.39) | POLBHPGDKDM4ENPSR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480204-A1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |