Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 4/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684092 | 0.71 | POLB (0.40) | POLBLRRK2MAOAMAOBERBB2 | |
| SCHEMBL9684667 | 0.69 | POLB (0.48) | POLBPDE10AMAOAMAOBERBB2 | |
| SCHEMBL9683351 | 0.69 | POLB (0.48) | POLBPDE10AMAOAMAOBERBB2 | |
| SCHEMBL19913900 | 0.67 | KDM4E (0.46) | POLBADORA1ADORA2AALDH1A1KMT2A | |
| SCHEMBL25225077 | 0.67 | KDM4E (0.41) | ERBB2ADORA1ALDH1A1KMT2AGAA | |
| SCHEMBL9040621 | 0.65 | MAOA (0.47) | POLBLRRK2MAOAMAOBERBB2 | |
| SCHEMBL28829325 | 0.64 | KDM4E (0.38) | ALDH1A1CYP2A6KMT2AMEN1MAPT | |
| SCHEMBL13437803 | 0.64 | GABRA1 (0.48) | ALDH1A1KMT2AGAAMEN1MAPT | |
| SCHEMBL19913901 | 0.64 | KDM4E (0.46) | POLBADORA1ADORA2APIM1ALDH1A1 | |
| SCHEMBL1905542 | 0.63 | ADORA1 (0.46) | POLBLRRK2ERBB2ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480204-A1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |