Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685475 | 0.83 | PPARD (0.46) | PPARDTSHRUGT2B7TDP1CA12 | |
| SCHEMBL3487454 | 0.82 | PPARD (0.57) | PPARDTSHRUGT2B7TP53TDP1 | |
| SCHEMBL13824600 | 0.80 | PPARD (0.55) | PPARDTSHRUGT2B7TDP1MAPT | |
| SCHEMBL13824850 | 0.80 | PPARD (0.55) | PPARDTSHRUGT2B7TDP1MAPT | |
| SCHEMBL10439377 | 0.79 | TSHR (0.56) | PPARDTSHRTP53TDP1CA12 | |
| SCHEMBL15011848 | 0.78 | PPARD (0.52) | PPARDTSHRUGT2B7TP53TDP1 | |
| SCHEMBL18979175 | 0.78 | PPARD (0.52) | PPARDTSHRUGT2B7TP53TDP1 | |
| SCHEMBL9683342 | 0.78 | PPARD (0.41) | PPARDTSHR | |
| SCHEMBL9683348 | 0.76 | PPARD (0.39) | PPARD | |
| SCHEMBL8839568 | 0.76 | PPARD (0.46) | PPARDTSHRUGT2B7TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |