Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8839568 | 0.92 | PPARD (0.46) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL9685456 | 0.85 | PPARD (0.40) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL9683406 | 0.83 | PPARD (0.59) | PPARDALDH1A1LMNATSHRMAPT | |
| SCHEMBL7185162 | 0.76 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10TSHRMAPT | |
| SCHEMBL9793608 | 0.75 | PPARD (0.39) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL9675367 | 0.74 | PPARD (0.37) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL9683342 | 0.74 | PPARD (0.41) | PPARDTSHR | |
| SCHEMBL10448229 | 0.74 | PPARD (0.38) | PPARDALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL13459987 | 0.73 | TDP1 (0.45) | ALDH1A1LMNAHSD17B10TSHRMAPT | |
| SCHEMBL5358516 | 0.73 | TDP1 (0.45) | ALDH1A1LMNAHSD17B10TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |