Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27371022 | 0.80 | DGAT1 (0.35) | DGAT1CYP2D6CA2CA12CA14 | |
| SCHEMBL19792256 | 0.78 | TDP1 (0.35) | DGAT1CYP2D6CA2CA12CA14 | |
| SCHEMBL27426176 | 0.78 | CYP2D6 (0.41) | DGAT1CYP2D6CA2CA12CA14 | |
| SCHEMBL27848464 | 0.78 | DGAT1 (0.34) | DGAT1CYP2D6CA2CA12CA14 | |
| SCHEMBL52466 | 0.77 | CA12 (0.35) | DGAT1CYP2D6CA2CA12CA14 | |
| SCHEMBL27425100 | 0.77 | CYP2D6 (0.40) | DGAT1CYP2D6CA2CA12CA14 | |
| SCHEMBL4553890 | 0.75 | DGAT1 (0.37) | DGAT1CYP2D6CA2CA12CA14 | |
| SCHEMBL1115385 | 0.75 | TDP1 (0.44) | DGAT1CYP2D6CA2CA12CA14 | |
| SCHEMBL6050243 | 0.75 | CA12 (0.34) | DGAT1CYP2D6CA2CA12CA14 | |
| SCHEMBL241533 | 0.75 | DGAT1 (0.46) | DGAT1CYP2D6CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467248-A2 | Pyrazolopyridine compound and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |