Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.37 |
| ▸ | UGCG | Q16739 | 2/20 | 0.37 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683725 | 1.00 | L3MBTL1 (0.44) | L3MBTL1TDP1TSHRIDO1SPHK1 | |
| SCHEMBL9683788 | 1.00 | L3MBTL1 (0.44) | L3MBTL1TDP1TSHRIDO1SPHK1 | |
| SCHEMBL8733833 | 0.87 | TSHR (0.50) | L3MBTL1TDP1TSHREPHX2HRH4 | |
| SCHEMBL2333457 | 0.80 | TSHR (0.54) | L3MBTL1TDP1TSHRIDO1HRH4 | |
| SCHEMBL4230078 | 0.80 | L3MBTL1 (0.54) | L3MBTL1TDP1TSHRIDO1EPHX2 | |
| SCHEMBL6268086 | 0.80 | L3MBTL1 (0.54) | L3MBTL1TDP1TSHRIDO1EPHX2 | |
| SCHEMBL27375031 | 0.80 | TSHR (0.54) | L3MBTL1TDP1TSHRIDO1HRH4 | |
| SCHEMBL8893085 | 0.80 | L3MBTL1 (0.54) | L3MBTL1TDP1TSHRIDO1EPHX2 | |
| SCHEMBL15923248 | 0.80 | L3MBTL1 (0.54) | L3MBTL1TDP1TSHRIDO1EPHX2 | |
| Hydrochloric Acid SCHEMBL20492261 | 0.79 | L3MBTL1 (0.53) | L3MBTL1TDP1TSHRIDO1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145844-A | Enzyme inhibitors, antiinflammatory agents, analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-09-08 | — | — | US | disclosed |
| US-5030733-A | Analgesics, antiinflammatory agents, phospholipase inhibitor | HOECHST-ROUSSEL PHARMACETICALS INCORPORATED (US) | 1991-07-09 | — | — | US | disclosed |