Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683751 | 0.97 | LMNA (0.35) | LMNABTKPTK2 | |
| SCHEMBL9857569 | 0.88 | LMNA (0.33) | LMNA | |
| SCHEMBL9417132 | 0.85 | LMNA (0.30) | LMNA | |
| SCHEMBL9685452 | 0.83 | BTK (0.32) | BTKPTK2 | |
| SCHEMBL9684225 | 0.80 | BTK (0.34) | BTKPTK2 | |
| SCHEMBL9417126 | 0.73 | — | — | |
| SCHEMBL9683673 | 0.73 | — | — | |
| SCHEMBL9683684 | 0.72 | — | — | |
| SCHEMBL9417131 | 0.71 | — | — | |
| SCHEMBL9857582 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |