Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199727 | 0.82 | RORC (0.50) | RORCTSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL199728 | 0.80 | RORC (0.58) | RORCTSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8845408 | 0.79 | POLB (0.50) | POLBGAAKDM4EMAPTGABRA1 | |
| SCHEMBL11415140 | 0.77 | TSHR (0.39) | RORCTSHRARGAAUSP2 | |
| SCHEMBL16051246 | 0.76 | RORC (0.53) | RORCTSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10794763 | 0.76 | RORC (0.42) | RORCTSHRARGAAUSP2 | |
| SCHEMBL342170 | 0.75 | TSHR (0.38) | RORCTSHRARGAAUSP2 | |
| SCHEMBL28180195 | 0.74 | RORC (0.56) | RORCTSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8616880 | 0.74 | CYP2C19 (0.63) | RORCPOLBTSHRCYP1A2CYP3A4 | |
| SCHEMBL2034981 | 0.73 | RORC (0.80) | RORCTSHRCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492473-A1 | Process for the preparation of 4-substituted 2,6-dialkylanilines | LONZA AG (CH) | 1992-07-01 | — | — | EP | disclosed |