⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20971474 | 0.75 | THRB (0.30) | — | |
| SCHEMBL10653516 | 0.75 | — | — | |
| SCHEMBL32680155 | 0.72 | — | — | |
| SCHEMBL1260717 | 0.70 | MEN1 (0.32) | — | |
| SCHEMBL30877160 | 0.70 | — | — | |
| SCHEMBL24621776 | 0.70 | — | — | |
| SCHEMBL23793324 | 0.69 | — | — | |
| SCHEMBL12087673 | 0.68 | — | — | |
| SCHEMBL4082432 | 0.67 | — | — | |
| SCHEMBL22042187 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254588-B1 | Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-01-15 | — | — | EP | claimed |
| EP-0254588-B1 | Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-01-15 | — | — | EP | disclosed |