Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683147 | 0.79 | KDM4E (0.32) | — | |
| SCHEMBL27186827 | 0.79 | HTT (0.42) | HTT | |
| SCHEMBL899232 | 0.75 | THRB (0.35) | — | |
| SCHEMBL1086194 | 0.73 | — | — | |
| SCHEMBL28410702 | 0.72 | HTT (0.31) | HTT | |
| SCHEMBL28835803 | 0.70 | HTT (0.34) | HTT | |
| SCHEMBL16683724 | 0.70 | HTT (0.35) | HTT | |
| SCHEMBL332287 | 0.69 | — | — | |
| SCHEMBL28803873 | 0.69 | — | — | |
| SCHEMBL20746309 | 0.68 | HTT (0.39) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254588-B1 | Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-01-15 | — | — | EP | claimed |
| EP-0254588-B1 | Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same | TOKYO TANABE COMPANY LIMITED (JP) | 1992-01-15 | — | — | EP | disclosed |