Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.40 |
| ▸ | PRKCG | P05129 | 2/20 | 0.40 |
| ▸ | PRKCB | P05771 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 2/20 | 0.40 |
| ▸ | PRKCH | P24723 | 2/20 | 0.40 |
| ▸ | PRKCI | P41743 | 2/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50962 | 0.92 | — | — | |
| SCHEMBL18194644 | 0.92 | — | — | |
| SCHEMBL51837 | 0.84 | — | — | |
| SCHEMBL12045201 | 0.84 | — | — | |
| Butyl Alcohol SCHEMBL10911261 | 0.82 | ALDH1A1 (0.79) | ALDH1A1PRKD3PRKCGPRKCBPRKCA | |
| Cetyl Alcohol SCHEMBL27495175 | 0.82 | ALDH1A1 (0.79) | ALDH1A1PRKD3PRKCGPRKCBPRKCA | |
| Butyl Alcohol SCHEMBL10911126 | 0.82 | ALDH1A1 (0.79) | ALDH1A1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL51216 | 0.82 | ALDH1A1 (0.58) | ALDH1A1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL51708 | 0.82 | ALDH1A1 (0.58) | ALDH1A1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL11243835 | 0.82 | ALDH1A1 (0.58) | ALDH1A1PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112784-A | Calcining magnesium and aluminum containing clay followed by rehydration, etherification catalysts | THE BRITISH PETROLEUM COMPANY P.L.C. (GB) | 1992-05-12 | — | — | US | disclosed |
| US-5110992-A | Process for the preparation of glycol ethers | THE BRITISH PETROLEUM CO., P.L.C. (GB) | 1992-05-05 | — | — | US | disclosed |
| EP-0421678-A1 | Process for the preparation of catalysts | The British Petroleum Company p.l.c. (GB) | 1991-04-10 | — | — | EP | disclosed |
| EP-0421679-A1 | Process for the preparation of glycol ethers | THE BRITISH PETROLEUM COMPANY P.L.C. (GB) | 1991-04-10 | — | — | EP | disclosed |
| EP-0421677-A1 | Process for the preparation of glycol ethers | THE BRITISH PETROLEUM COMPANY P.L.C. (GB) | 1991-04-10 | — | — | EP | disclosed |