Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3502512 | 0.93 | — | — | |
| SCHEMBL29902944 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MAPK1FOLH1CYP2D6CYP2C19 | |
| SCHEMBL2344568 | 0.83 | — | — | |
| SCHEMBL23640298 | 0.82 | ALDH1A1 (0.71) | ALDH1A1KDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL3174690 | 0.80 | KDM4E (0.50) | ALDH1A1KDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL23378216 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL2029681 | 0.77 | KDM4E (0.55) | ALDH1A1KDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL5569558 | 0.77 | KDM4E (0.55) | ALDH1A1KDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL20836564 | 0.77 | KDM4E (0.55) | ALDH1A1KDM4EMAPK1HIF1AMEN1 | |
| SCHEMBL15871737 | 0.77 | KDM4E (0.55) | ALDH1A1KDM4EMAPK1HIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509795-A2 | Carbamates of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-21 | — | — | EP | disclosed |
| US-5118678-A | Antibody inhibitors, antiinflammatory agents, fungicides, antitumor agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |