Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.60 |
| ▸ | PTPRC | P08575 | 2/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 6/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.47 |
| ▸ | CSNK2A3 | Q8NEV1 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599578 | 0.85 | TTR (0.81) | TTRPTPRCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL31086890 | 0.81 | TTR (0.80) | TTRPTPRCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL71021 | 0.81 | TTR (0.88) | TTRPTPRCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL31436145 | 0.81 | TTR (0.88) | TTRPTPRCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL598301 | 0.81 | TTR (0.88) | TTRPTPRCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6901581 | 0.81 | TTR (0.80) | TTRPTPRCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL600296 | 0.81 | TTR (0.80) | TTRPTPRCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29036115 | 0.81 | MCL1 (0.46) | MAPTHPGDCDC25ACDC25BS100A4 | |
| Ammonia Solution, Strong SCHEMBL11846203 | 0.79 | TTR (0.77) | TTRPTPRCCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL8954247 | 0.79 | TTR (0.66) | TTRPTPRCCSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |