SCHEMBL6901581

SCHEMBL6901581

O=C(O)c1ccc2c(c1)-c1cc(C(=O)O)ccc1C2=O

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 5/20 0.80
PTPRC P08575 2/20 0.77
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
MAPT P10636 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
HPGD P15428 1/20 0.58
CDC25A P30304 1/20 0.58
CDC25B P30305 1/20 0.58
CTDSP1 Q9GZU7 1/20 0.58
CHEK1 O14757 1/20 0.58
POLB P06746 3/20 0.55
CSNK2A2 P19784 5/20 0.54
CSNK2B P67870 5/20 0.54
CSNK2A1 P68400 5/20 0.54
CSNK2A3 Q8NEV1 5/20 0.54
S100A4 P26447 1/20 0.52
ALDH1A1 P00352 1/20 0.51
THRB P10828 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599578 0.96 TTR (0.81) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL31436145 0.95 TTR (0.88) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL598301 0.95 TTR (0.88) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL71021 0.95 TTR (0.88) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL3100326 0.92 PTPRC (0.92) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL31086890 0.91 TTR (0.80) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL600296 0.91 TTR (0.80) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL30610011 0.89 TTR (1.00) TTRPTPRCKMT2AMEN1MAPT
SCHEMBL123492 0.89 TTR (1.00) TTRPTPRCKMT2AMEN1MAPT
Ammonia Solution, Strong SCHEMBL11846203 0.88 TTR (0.77) TTRPTPRCKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160124330-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR MANUFACTURING THE SAME, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-05-05 US disclosed
US-6710202-B2 ESTERIFYING CRUDE TEREPHTHALIC ACID WITH ETHYLENE GLYCOL AND/OR ETHYLENE OXIDE, MIXING THE REACTION PRODUCT OBTAINED WITH ETHYLENE GLYCOL AND DEIONIZING THE SOLUTION, DISTILLING OFF LOWER BOILING SUBSTANCES, MOLECULAR DISTILLATION AIES CO., LTD. (JP) 2004-03-23 US disclosed
US-20030050499-A1 Process for production of high-purity bis-beta-hydroxyethyl terephthalate PET REBIRTH CO., LTD. (JP) 2003-03-13 US disclosed
EP-1254888-A1 PROCESS FOR PRODUCTION OF HIGH-PURITY BIS-BETA-HYDROXYETHYL TEREPHTHALATE Aies Co., Ltd. (JP) 2002-11-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030050499-A1 Process for production of high-purity bis-beta-hydroxyethyl terephthalate FHIT, DBH, RPS27A TTR 740/4885PTPRC 4034/4885KMT2A 2056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.