Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392903 | 1.00 | ALDH1A1 (0.47) | ALDH1A1BCHEACHECCR6PAX8 | |
| SCHEMBL392184 | 0.99 | ALDH1A1 (0.49) | ALDH1A1BCHEACHECCR6PAX8 | |
| SCHEMBL390750 | 0.94 | ALDH1A1 (0.50) | ALDH1A1CCR6PAX8F13A1TGM2 | |
| SCHEMBL28002371 | 0.89 | HTT (0.50) | ALDH1A1BCHEACHECCR6PAX8 | |
| SCHEMBL392019 | 0.89 | HTT (0.50) | ALDH1A1BCHEACHECCR6PAX8 | |
| SCHEMBL391715 | 0.89 | ALDH1A1 (0.53) | ALDH1A1CCR6PAX8F13A1TGM2 | |
| SCHEMBL389007 | 0.87 | HTT (0.51) | ALDH1A1BCHEACHECCR6PAX8 | |
| SCHEMBL21235957 | 0.86 | CCR6 (0.48) | ALDH1A1BCHEACHECCR6PAX8 | |
| SCHEMBL132476 | 0.85 | ABCB1 (0.49) | ALDH1A1BCHEACHECCR6PAX8 | |
| SCHEMBL9232890 | 0.85 | ABCB1 (0.49) | ALDH1A1BCHEACHECCR6PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513703-A2 | Carbamate esters of eseroline having anticholinesterase activity, a process for their preparation and relative pharmaceutical compositions containing them as the active principle | MAGIS FARMACEUTICI S.p.A. (IT) | 1992-11-19 | — | — | EP | disclosed |