Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | EEF2K | O00418 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263474 | 0.80 | PTGS2 (0.64) | GAAEEF2KSRCPTGS2PTGS1 | |
| SCHEMBL3263476 | 0.80 | PTGS2 (0.64) | GAAEEF2KSRCPTGS2PTGS1 | |
| SCHEMBL7698651 | 0.77 | PTGS2 (0.57) | GAAEEF2KSRCPTGS2PTGS1 | |
| SCHEMBL7698649 | 0.77 | PTGS2 (0.57) | GAAEEF2KSRCPTGS2PTGS1 | |
| SCHEMBL7193575 | 0.75 | PTGS2 (0.70) | GAAEEF2KSRCPTGS2PTGS1 | |
| SCHEMBL8536499 | 0.73 | PTGS2 (0.55) | GAAEEF2KSRCPTGS2PTGS1 | |
| SCHEMBL8536501 | 0.73 | PTGS2 (0.55) | GAAEEF2KSRCPTGS2PTGS1 | |
| SCHEMBL10369603 | 0.72 | PTGS2 (0.58) | EEF2KSRCPTGS2PTGS1CYP1A2 | |
| SCHEMBL10369604 | 0.72 | PTGS2 (0.58) | EEF2KSRCPTGS2PTGS1CYP1A2 | |
| SCHEMBL8822313 | 0.72 | PTGS2 (0.61) | GAAEEF2KSRCPTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500337-A1 | Composition containing aryl-substituted rhodanine derivatives for the treatment of type I diabetes | UNIVERSITY OF COLORADO FOUNDATION, INC. (US) | 1992-08-26 | — | — | EP | disclosed |