Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787439 | 0.85 | ABCB1 (0.46) | ABCB1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL9787435 | 0.85 | ABCB1 (0.46) | ABCB1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL9684235 | 0.83 | KCNH2 (0.34) | ABCB1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL9684229 | 0.83 | KCNH2 (0.34) | ABCB1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL10822546 | 0.82 | HDAC6 (0.38) | LMNAALDH1A1 | |
| SCHEMBL10822385 | 0.82 | HDAC6 (0.38) | LMNAALDH1A1 | |
| SCHEMBL9685324 | 0.82 | ADRB3 (0.54) | ADRB2ADRB1ADRB3MTNR1AMTNR1B | |
| SCHEMBL9684062 | 0.81 | ABCB1 (0.50) | ABCB1ADRB1ADRB3POLBLMNA | |
| SCHEMBL9684073 | 0.81 | ABCB1 (0.50) | ABCB1ADRB1ADRB3POLBLMNA | |
| SCHEMBL9684301 | 0.79 | ABCB1 (0.44) | ABCB1ADRB2ADRB1ADRB3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |