Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787439 | 1.00 | ABCB1 (0.46) | ABCB1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL9684099 | 0.89 | ABCB1 (0.42) | ABCB1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL9684091 | 0.89 | ABCB1 (0.42) | ABCB1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL9684909 | 0.85 | ABCB1 (0.43) | ABCB1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL9684301 | 0.84 | ABCB1 (0.44) | ABCB1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL9684307 | 0.84 | ABCB1 (0.44) | ABCB1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL9683733 | 0.81 | ABCB1 (0.36) | ABCB1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL9683741 | 0.81 | ABCB1 (0.36) | ABCB1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL10822884 | 0.81 | AOC3 (0.43) | MEN1GAAKMT2APRSS1TMPRSS15 | |
| SCHEMBL10822878 | 0.81 | AOC3 (0.43) | MEN1GAAKMT2APRSS1TMPRSS15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |