Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685356 | 1.00 | ADRB3 (0.60) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL9684291 | 0.85 | ADRB3 (0.61) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL9684286 | 0.85 | ADRB3 (0.61) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL9685359 | 0.83 | ADRB3 (0.64) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9683325 | 0.83 | ADRB3 (0.64) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL9684195 | 0.83 | ADRB3 (0.64) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL9684201 | 0.83 | ADRB3 (0.64) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9683322 | 0.83 | ADRB3 (0.64) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL9685355 | 0.83 | ADRB3 (0.64) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL9812077 | 0.83 | ADRB3 (0.64) | ADRB3ADRB1ADRB2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |