SCHEMBL9685375

SCHEMBL9685375

CC(=O)Oc1ccccn1.O=C(Oc1ccccn1)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.41
TSHR P16473 4/20 0.41
CYP3A4 P08684 2/20 0.41
LMNA P02545 2/20 0.41
ESR1 P03372 2/20 0.41
HIF1A Q16665 2/20 0.41
ABCB11 O95342 1/20 0.41
ADRA2A P08913 1/20 0.41
CYP2C9 P11712 1/20 0.41
PDE4A P27815 1/20 0.41
ADRA1A P35348 1/20 0.41
OPRK1 P41145 1/20 0.41
STAT6 P42226 1/20 0.41
SLC6A3 Q01959 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
ALDH1A1 P00352 4/20 0.40
MAPT P10636 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
ALOX12 P18054 1/20 0.35
BACE1 P56817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3170356 0.92 KDM4E (0.40) KDM4ETSHRLMNAHIF1AALDH1A1
Methylamine SCHEMBL20479964 0.90 TSHR (0.40) KDM4ETSHRCYP3A4LMNAESR1
SCHEMBL680046 0.87 KDM4E (0.50) KDM4ETSHRCYP3A4LMNAESR1
SCHEMBL29721865 0.87 KDM4E (0.50) KDM4ETSHRCYP3A4LMNAESR1
Hydrochloric Acid SCHEMBL711904 0.85 KDM4E (0.49) KDM4ETSHRCYP3A4LMNAESR1
SCHEMBL11122315 0.85 KDM4E (0.49) KDM4ETSHRCYP3A4LMNAESR1
Dimethylamine SCHEMBL3686153 0.82 KDM4E (0.46) KDM4ETSHRCYP3A4LMNAESR1
Formic Acid SCHEMBL28236591 0.80 KDM4E (0.45) KDM4ETSHRCYP3A4LMNAESR1
SCHEMBL11717509 0.78 ELANE (0.47) TSHRLMNAALDH1A1NPC1RAB9A
Maleic Acid SCHEMBL27920212 0.78 KDM4E (0.44) KDM4ETSHRCYP3A4LMNAESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0204535-B1 N-FLUOROPYRIDINIUM SALT AND PROCESS FOR PREPARING SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-08-19 EP disclosed
EP-0204535-A1 N-fluoropyridinium salt and process for preparing same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-12-10 EP disclosed