⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96859 | 1.00 | — | — | |
| SCHEMBL6298116 | 0.96 | — | — | |
| SCHEMBL6298115 | 0.96 | — | — | |
| SCHEMBL1760673 | 0.76 | — | — | |
| SCHEMBL110025 | 0.76 | — | — | |
| SCHEMBL1760717 | 0.76 | — | — | |
| SCHEMBL5328842 | 0.76 | — | — | |
| SCHEMBL425874 | 0.76 | — | — | |
| SCHEMBL27683 | 0.76 | — | — | |
| SCHEMBL733279 | 0.71 | ALDH1A1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240148699-A1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-05-09 | — | — | US | disclosed |
| US-20240140975-A1 | ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG | XINJIANG TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2024-05-02 | — | — | US | disclosed |
| US-11919923-B2 | Antiviral application of nucleoside analog or combination formulation containing nucleoside analog | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2024-03-05 | — | — | US | disclosed |
| US-11731965-B2 | Tetrahydroprotoberberine compound, preparation method therefor and uses thereof, and pharmaceutical composition | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2023-08-22 | — | — | US | disclosed |
| US-20230219993-A1 | ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG | VIGONVITA LIFE SCIENCES CO., LTD. (CN) | 2023-07-13 | — | — | US | disclosed |
| WO-2023104213-A1 | CYCLIC BISBENZYL TETRAHYDROISOQUINOLINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2023-06-15 | — | — | WO | disclosed |
| EP-4141007-A1 | ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-03-01 | — | — | EP | disclosed |
| CN-115448924-A | Application of nucleoside analogue or combination preparation containing nucleoside analogue in resisting virus | 中国科学院上海药物研究所 | 2022-12-09 | — | — | CN | disclosed |
| CN-114096543-B | Application of nucleoside analogue or combination preparation containing nucleoside analogue in resisting virus | 中国科学院上海药物研究所 | 2022-08-16 | — | — | CN | disclosed |
| US-11384112-B2 | Artificial nucleoside and artificial nucleotide, and artificial oligonucleotide | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2022-07-12 | — | — | US | disclosed |
| US-20010012596-A1 | For resist applications; thermostability, storage stability | CIBA SPECIALTY CHEMICALS CORP. | 2001-08-09 | — | — | US | disclosed |
| EP-1095029-A1 | PIPERAZINE DERIVATIVES INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | UNIVERSITE PARIS 7 - Denis DIDEROT (FR) | 2001-05-02 | — | — | EP | disclosed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-6022906-A | α-aminoacetophenone photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-08 | — | — | US | disclosed |
| WO-2000001677-A1 | PIPERAZINE DERIVATIVES INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | UNIVERSITE PARIS 7 - DENIS DIDEROT (FR) | 2000-01-13 | — | — | WO | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |
| US-4914116-A | Nitrogen-containing heterocyclic compounds, and their use as insecticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4847259-A | Nitrogen-containing heterocyclic compounds, and use as insecticide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| US-4714706-A | JUVENILE HORMONE INHIBITORS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-12-22 | — | — | US | disclosed |
| EP-0203798-A2 | Nitrogen-containing heterocyclic compounds, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-12-03 | — | — | EP | disclosed |