Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.57 |
| ▸ | PTPRC | P08575 | 1/20 | 0.55 |
| ▸ | BCL2 | P10415 | 6/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29036115 | 0.85 | MCL1 (0.46) | S100A4BCL2MCL1MAOAMAOB | |
| SCHEMBL19767754 | 0.83 | S100A4 (0.81) | S100A4PTPRCBCL2MCL1MAOA | |
| SCHEMBL9811057 | 0.82 | ELANE (0.53) | S100A4PTPRCBCL2MCL1MAOA | |
| SCHEMBL11294862 | 0.80 | ELANE (0.55) | S100A4PTPRCBCL2MCL1MAOA | |
| SCHEMBL16659000 | 0.79 | S100A4 (0.90) | S100A4PTPRCBCL2MCL1MAOA | |
| SCHEMBL762135 | 0.79 | S100A4 (0.80) | S100A4PTPRCBCL2MCL1MAOA | |
| SCHEMBL12469932 | 0.79 | S100A4 (0.71) | S100A4PTPRCBCL2MCL1MAOA | |
| SCHEMBL29664078 | 0.79 | S100A4 (0.80) | S100A4PTPRCBCL2MCL1MAOA | |
| SCHEMBL30363166 | 0.79 | S100A4 (0.71) | S100A4PTPRCBCL2MCL1MAOA | |
| SCHEMBL3717374 | 0.79 | S100A4 (0.80) | S100A4PTPRCBCL2MCL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |