Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FABP2 | P12104 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20565193 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TSHRPPARACYP2D6CYP2C19 | |
| Bicarbonate SCHEMBL28464828 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL10253908 | 0.75 | GAA (0.35) | ALDH1A1TSHR | |
| SCHEMBL29232723 | 0.75 | TSHR (0.42) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL26973338 | 0.75 | TSHR (0.42) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL7417635 | 0.75 | TSHR (0.42) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL8930064 | 0.73 | TSHR (0.47) | ALDH1A1TSHRPPARACYP2D6CYP2C19 | |
| Acetic Acid SCHEMBL927068 | 0.73 | FFAR3 (0.50) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL1966966 | 0.73 | TSHR (0.47) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL18135533 | 0.73 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089980-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2018-01-31 | — | — | EP | disclosed |
| EP-2692796-A1 | COMPOSITION | Sumitomo Chemical Co., Ltd (JP) | 2014-02-05 | — | — | EP | disclosed |
| CN-1766733-A | Phototonus resin composition, spacer for display panel and display panel | JSR CORP (JP) | 2006-05-03 | — | — | CN | disclosed |
| EP-0481081-A1 | LAMINATE, HEAT-SHRINKING LAMINATE FILM, AND FOAMED LAMINATE | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |