SCHEMBL9686155

SCHEMBL9686155

COc1cc(C=O)ccc1OC(C)(OC)OC

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.68
TSHR P16473 1/20 0.68
FDPS P14324 1/20 0.58
TTR P02766 1/20 0.54
HPGD P15428 2/20 0.53
AOX1 Q06278 1/20 0.53
TRIM24 O15164 1/20 0.53
ALDH5A1 P51649 1/20 0.53
ABAT P80404 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
TRIM33 Q9UPN9 1/20 0.53
POLB P06746 1/20 0.51
MAPT P10636 5/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
HTT P42858 2/20 0.48
LMNA P02545 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2583316 0.86 ALDH1A1 (0.72) ALDH1A1TSHRFDPSTTRHPGD
3,4-Dimethoxybenzaldehyde SCHEMBL29364994 0.82 ALDH1A1 (1.00) ALDH1A1TSHRFDPSTTRHPGD
3,4-Dimethoxybenzaldehyde SCHEMBL5308959 0.82 ALDH1A1 (1.00) ALDH1A1TSHRFDPSTTRHPGD
3,4-Dimethoxybenzaldehyde SCHEMBL1330962 0.82 ALDH1A1 (1.00) ALDH1A1TSHRFDPSTTRHPGD
3,4-Dimethoxybenzaldehyde SCHEMBL25202 0.82 ALDH1A1 (1.00) ALDH1A1TSHRFDPSTTRHPGD
SCHEMBL28445133 0.81 ALDH1A1 (0.70) ALDH1A1TSHRFDPSTTRHPGD
SCHEMBL30049249 0.81 ALDH1A1 (0.70) ALDH1A1TSHRFDPSTTRHPGD
SCHEMBL18239636 0.81 ALDH1A1 (0.70) ALDH1A1TSHRFDPSTTRHPGD
3,4-Dimethoxybenzaldehyde SCHEMBL29624454 0.80 ALDH1A1 (0.96) ALDH1A1TSHRFDPSTTRHPGD
3,4-Dimethoxybenzaldehyde SCHEMBL28205798 0.80 ALDH1A1 (0.96) ALDH1A1TSHRFDPSTTRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0506231-A1 Smoking composition containing a flavorant-release saccharide additive Philip Morris Products Inc. (US) 1992-09-30 EP disclosed