Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685805 | 0.97 | SLC6A9 (0.61) | SLC6A9ALDH1A1TP53CHRM5CHRM1 | |
| Fumaric Acid SCHEMBL9634790 | 0.92 | SLC6A9 (0.55) | SLC6A9ALDH1A1TP53CHRM5CHRM1 | |
| SCHEMBL9634663 | 0.90 | SLC6A9 (0.56) | SLC6A9ALDH1A1TP53MEN1TSHR | |
| Fumaric Acid SCHEMBL9634676 | 0.89 | SLC6A9 (0.56) | SLC6A9ALDH1A1TP53CHRM5CHRM1 | |
| SCHEMBL9686512 | 0.88 | SLC6A9 (0.68) | SLC6A9ALDH1A1CHRM5CHRM1MEN1 | |
| Oxalic Acid SCHEMBL9870147 | 0.87 | SLC6A9 (0.66) | SLC6A9ALDH1A1TP53CHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9870156 | 0.87 | SLC6A9 (0.66) | SLC6A9ALDH1A1TP53CHRM5CHRM1 | |
| SCHEMBL9687058 | 0.86 | SLC6A9 (0.57) | SLC6A9ALDH1A1TP53MEN1TSHR | |
| SCHEMBL9635884 | 0.86 | SLC6A9 (0.64) | SLC6A9ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL9685783 | 0.84 | SLC6A9 (0.64) | SLC6A9ALDH1A1CHRM5CHRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307014-B1 | ANTI-ALLERGIC 2-(HETEROCYCLYL ALKYL) IMIDAZO PYRIDINES AND 2-(HETEROCYCLYL ALKYL) PURINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-09 | — | — | EP | disclosed |
| US-4946843-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-08-07 | — | — | US | disclosed |