Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.45 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686211 | 0.86 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1TP53HIF1ATDP1 | |
| SCHEMBL7525964 | 0.86 | TDP1 (0.52) | SMN1; SMN2ALDH1A1TDP1POLBHSD17B10 | |
| SCHEMBL16602991 | 0.83 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1TP53TDP1POLB | |
| SCHEMBL18622117 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1TP53HIF1ATDP1 | |
| SCHEMBL12719477 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1TDP1POLBHSD17B10 | |
| SCHEMBL25140172 | 0.78 | POLB (0.54) | SMN1; SMN2ALDH1A1TDP1POLBHSD17B10 | |
| SCHEMBL2336203 | 0.77 | POLB (0.68) | SMN1; SMN2ALDH1A1TDP1POLBHSD17B10 | |
| SCHEMBL29990241 | 0.77 | POLB (0.68) | SMN1; SMN2ALDH1A1TDP1POLBHSD17B10 | |
| SCHEMBL377420 | 0.77 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1TP53TDP1POLB | |
| SCHEMBL864429 | 0.77 | SMN1; SMN2 (0.79) | SMN1; SMN2ALDH1A1HTTL3MBTL1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |