M-Xylene

M-Xylene

SCHEMBL9686508

CC(=O)OCc1cccc(C)c1.Cc1cccc(C)c1

nearest known ligand 0.61

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.61
MAOB P27338 5/20 0.56
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55
MMP12 P39900 1/20 0.55
IDO1 P14902 2/20 0.55
POLB P06746 1/20 0.51
CYP3A4 P08684 1/20 0.49
LMNA P02545 1/20 0.49
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TACR1 P25103 1/20 0.47
HSP90AA1 P07900 1/20 0.46
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
FFAR4 Q5NUL3 1/20 0.46
MAOA P21397 1/20 0.45
CTBP2 P56545 1/20 0.45
ELANE P08246 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6903259 0.98 ALDH1A1 (0.63) ALDH1A1MAOBMMP2MMP9MMP12
SCHEMBL6709375 0.87 ALDH1A1 (0.73) ALDH1A1MAOBCYP3A4KMT2A
SCHEMBL3763603 0.85 IDO1 (0.58) MAOBMMP2MMP9MMP12IDO1
SCHEMBL9685714 0.84 ALDH1A1 (0.47) ALDH1A1MAOBMMP2MMP9MMP12
SCHEMBL20267801 0.83 IDO1 (0.60) ALDH1A1MAOBMMP2MMP9MMP12
SCHEMBL9686081 0.83 ALDH1A1 (0.55) ALDH1A1CYP3A4LMNATACR1FFAR4
SCHEMBL5971176 0.83 ALDH1A1 (0.55) ALDH1A1CYP3A4LMNATACR1FFAR4
SCHEMBL11237868 0.82 ALDH1A1 (0.61) ALDH1A1MAOBMMP2MMP9MMP12
SCHEMBL7656159 0.82 IDO1 (0.59) MAOBMMP2MMP9MMP12IDO1
SCHEMBL2535662 0.82 HSP90AA1 (0.59) ALDH1A1MAOBMMP2MMP9MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5078838-A By electrochemical anodic oxidation of benzyl derivatives in the presence of an aliphatic alcohol BASF AKTIENGESELLSCHAFT (DE) 1992-01-07 US disclosed