SCHEMBL9686789

SCHEMBL9686789

Cc1cc[c]cc1Oc1ccccn1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
TSHR P16473 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAP4K4 O95819 1/20 0.35
DRD1 P21728 2/20 0.34
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
CD274 Q9NZQ7 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
CCR1 P32246 1/20 0.33
CCR5 P51681 1/20 0.33
CCR8 P51685 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9685365 0.82 KDM4E (0.44) KDM4EMEN1KMT2AMAP4K4PDE4A
SCHEMBL9722803 0.82 KDM4E (0.44) KDM4ETSHRNPC1RAB9ASMN1; SMN2
SCHEMBL9685468 0.82 KDM4E (0.47) KDM4EKMT2ANPC1RAB9AMAP4K4
SCHEMBL4799563 0.80 SMN1; SMN2 (0.62) KDM4ETSHRMEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL2964219 0.79 SMN1; SMN2 (0.60) KDM4ETSHRMEN1KMT2ANPC1
SCHEMBL694049 0.79 KDM4E (0.44) KDM4EKMT2ANPC1MAP4K4LMNA
SCHEMBL693615 0.79 KDM4E (0.44) KDM4EMEN1KMT2AMAP4K4PDE4A
SCHEMBL27729045 0.76 KDM4E (0.42) KDM4EMEN1KMT2AMAP4K4CD274
SCHEMBL11138427 0.73 KDM4E (0.66) KDM4ETSHRMEN1KMT2ANPC1
SCHEMBL692949 0.73 LTA4H (0.46) KDM4ENPC1RAB9ASMN1; SMN2MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1032005-C Novel silane derivatives, formulations containing them and their use as pesticides HOECHST AG (DE) 1996-06-12 CN disclosed
CN-1027448-C Heterocyclic neophenan analogs and their use as anti-inflammatory agents HOECHST AG (DE) 1995-01-18 CN disclosed
CN-1091425-A Heterocyclic neophenan analogs, process for their preparation and their use as pesticides HOECHST AG (DE) 1994-08-31 CN disclosed
CN-1025501-C Process for preparing silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
CN-1025502-C Process for preparing silane derivatives HOECHST AG (DE) 1994-07-20 CN disclosed
EP-0288810-B1 HETEROCYCLIC NEOPHANE ANALOGS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-02 EP disclosed
US-5116826-A SILAZANEOPHYL SULFIDES, AND THEIR USE AS PESTICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed
US-5002957-A Insecticides, acaricides, nematocides HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-26 US disclosed
US-4990621-A Insecticides, miticides and nematocides; 3-(3-fluoro-4-phenoxyphenyl, 3-(5-fluoro-3-phenoxypyrid-2-yl) or 3-(3-methyl-4-phenyl prop-1-ene HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed
US-4966902-A INSECTICIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1990-10-30 US disclosed
CN-1036570-A The new silylation sulfide of new alkyl sulfur compounds of azepine and azepine, they the preparation method, contain their preparation and they are as the application of sterilant HOECHST AG (DE) 1989-10-25 CN disclosed
EP-0336199-A1 Azaneophyl and silazaneophyl sulfides, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1989-10-11 EP disclosed
US-4864027-A INSECTICIDES, NEMATOCIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1989-09-05 US disclosed
EP-0288810-A1 Heterocyclic neophane analogs, processes for their preparation and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-02 EP disclosed
CN-88102112-A Heterocyclic neophenan analogs, process for their preparation and their use as pesticides 1988-10-26 CN disclosed
US-4775664-A INSECTICIDES, MITICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1988-10-04 US disclosed
CN-87102981-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1988-03-02 CN disclosed
EP-0249015-A1 Silane derivatives, process for their preparation, agents containing them, and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-12-16 EP disclosed
CN-86107292-A Novel silane derivatives, process for their preparation, formulations containing them and their use as pesticides 1987-07-29 CN disclosed
EP-0224024-A1 Silane derivatives, process for their preparation, agents containing them and their use as pesticides HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP disclosed