Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14174627 | 0.82 | MAPT (0.43) | HTTMAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL4266171 | 0.77 | HTT (0.53) | HTTMAPTSMN1; SMN2POLBMEN1 | |
| SCHEMBL24271913 | 0.77 | HTT (0.41) | HTTMAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL11360625 | 0.77 | MAPT (0.42) | HTTMAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL19364256 | 0.71 | HTT (0.42) | HTTMAPTSMN1; SMN2ACACBALDH1A1 | |
| SCHEMBL9686368 | 0.71 | LMNA (0.37) | MAPTLMNAKMT2AALDH1A1 | |
| SCHEMBL13576998 | 0.67 | HTT (0.46) | HTTMAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL29761634 | 0.67 | HTT (0.46) | HTTMAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL21017076 | 0.67 | SMN1; SMN2 (0.48) | HTTMAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL9373222 | 0.66 | HTT (0.45) | HTTMAPTSMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1091425-A | Heterocyclic neophenan analogs, process for their preparation and their use as pesticides | HOECHST AG (DE) | 1994-08-31 | — | — | CN | disclosed |
| EP-0288810-B1 | HETEROCYCLIC NEOPHANE ANALOGS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-02 | — | — | EP | disclosed |
| US-4966902-A | INSECTICIDES, MITICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-30 | — | — | US | disclosed |