⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867084 | 0.78 | — | — | |
| Methoxymethane SCHEMBL10627012 | 0.74 | CHRM2 (0.31) | — | |
| SCHEMBL14986454 | 0.73 | — | — | |
| SCHEMBL13006245 | 0.72 | — | — | |
| SCHEMBL967838 | 0.71 | — | — | |
| SCHEMBL317280 | 0.69 | — | — | |
| SCHEMBL966548 | 0.69 | — | — | |
| SCHEMBL6327737 | 0.69 | — | — | |
| SCHEMBL5258 | 0.67 | — | — | |
| SCHEMBL1792611 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030868-B2 | Prodrugs of CGRP antagonists | PFIZER IRELAND PHARMACEUTICALS (IE) | 2024-07-09 | — | — | US | disclosed |
| US-20240067651-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. | 2024-02-29 | — | — | US | disclosed |
| CN-114945573-A | Prodrugs of myeloperoxidase inhibitors | 拜奥海芬治疗学有限公司 | 2022-08-26 | — | — | CN | disclosed |
| US-11390604-B2 | Imidazole-pyrazole derivatives | HOFFMANN-LA ROCHE INC. (US) | 2022-07-19 | — | — | US | disclosed |
| EP-3934756-A1 | NOVEL IMIDAZOLE-PYRAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2022-01-12 | — | — | EP | disclosed |
| US-20210395223-A1 | PRODRUGS OF CGRP ANTAGONISTS | PFIZER IRELAND PHARMACEUTICALS (IE) | 2021-12-23 | — | — | US | disclosed |
| CN-113613722-A | Novel imidazole-pyrazole derivatives | 豪夫迈·罗氏有限公司 | 2021-11-05 | — | — | CN | disclosed |
| EP-3863629-A1 | PRODRUGS OF CGRP ANTAGONISTS | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2021-08-18 | — | — | EP | disclosed |
| CN-112888438-A | Prodrugs of CGRP antagonists | 拜尔哈文制药股份有限公司 | 2021-06-01 | — | — | CN | disclosed |
| WO-2021072140-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. (US) | 2021-04-15 | — | — | WO | disclosed |
| US-4828973-A | DIRECT POSITIVES WITH REVERSAL PROPERTIES | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0189774-B1 | PROCESS FOR PRODUCTION OF N,N-DISUBSTITUTED CARBOXYLIC ACID AMIDES | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1989-04-12 | — | — | EP | disclosed |
| EP-0303301-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |
| US-4801520-A | DEVELOPMENT-INHIBITOR-RELEASING COUPLER; UNFOGGED INTERNAL LATENT IMAGE-TYPE SILVER HALIDE PARTICLES DEVELOPED AT A LOW PH; STORAGE STABLE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-01-31 | — | — | US | disclosed |
| US-4789627-A | USING AROMATIC AMINE DEVELOPER PRESENCE OF NUCLEATING AGENT AND/OF FOGGING WHILE CONTROLLING PH | FUJI PHOTO FILM CO., LTD. (JP) | 1988-12-06 | — | — | US | disclosed |
| EP-0276842-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |
| EP-0249239-A2 | Process for the formation of direct positive images | FUJI PHOTO FILM CO., LTD. (JP) | 1987-12-16 | — | — | EP | disclosed |
| EP-0189774-A1 | Process for production of N,N-disubstituted carboxylic acid amides | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | disclosed |
| US-4428766-A | 2N-1,2,4,6,Thiatriazine-1,1-dioxides and their use for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| US-4343648-A | 6H-1,2,4,6-THIATRIAZINE-1,1-DIOXIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-10 | — | — | US | disclosed |