Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.66 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15512374 | 0.90 | ALDH1A1 (0.65) | ALDH1A1POLBTDP1GAAMAPT | |
| SCHEMBL15499938 | 0.90 | ALDH1A1 (0.65) | ALDH1A1POLBTDP1GAAMAPT | |
| SCHEMBL16435297 | 0.90 | ALDH1A1 (0.65) | ALDH1A1POLBTDP1GAAMAPT | |
| Hydrochloric Acid SCHEMBL15512665 | 0.89 | ALDH1A1 (0.63) | ALDH1A1POLBTDP1GAAMAPT | |
| Hydrochloric Acid SCHEMBL15512666 | 0.89 | ALDH1A1 (0.63) | ALDH1A1POLBTDP1GAAMAPT | |
| SCHEMBL28391662 | 0.87 | ALDH1A1 (0.60) | ALDH1A1POLBTDP1GAAMAPT | |
| Hydrochloric Acid SCHEMBL28178151 | 0.86 | ALDH1A1 (0.59) | ALDH1A1POLBTDP1GAAMAPT | |
| SCHEMBL9784820 | 0.84 | SMN1; SMN2 (0.63) | ALDH1A1POLBTDP1GAAMAPT | |
| Dibemethine SCHEMBL9416520 | 0.81 | NPC1 (0.63) | ALDH1A1SMN1; SMN2NPC1RAB9AMEN1 | |
| Dibemethine SCHEMBL9416516 | 0.81 | NPC1 (0.63) | ALDH1A1SMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385422-B1 | 1,4-DIHYDRO-5-ISOPROPOXY-2-METHYL-4-(2-TRIFLUORMETHYLPHENYL)-1,6-NAPHTHYRIDINE-3-CARBOXYACID-(2-(N-METHYL-N-PHENYLMETHYL-AMINO)-ETHYL)ESTER FUMARATE | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1992-07-29 | — | — | EP | claimed |
| US-5039679-A | Cardiovascular disorders | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1991-08-13 | — | — | US | disclosed |