O-Xylene

O-Xylene

SCHEMBL9686891

CCOCCOC(C)=O.Cc1ccccc1C

nearest known ligand 0.68

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.68
TSHR P16473 2/20 0.68
THRB P10828 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 1/20 0.45
HSD17B10 Q99714 1/20 0.45
RAD52 P43351 1/20 0.44
TDP1 Q9NUW8 1/20 0.42
HTT P42858 1/20 0.42
GAA P10253 2/20 0.41
DHODH Q02127 1/20 0.40
HRH1 P35367 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL10600132 0.88 ALDH1A1 (0.66) ALDH1A1TSHRTHRBSMN1; SMN2LMNA
Biphenyl SCHEMBL28797140 0.86 ALDH1A1 (0.68) ALDH1A1TSHRTHRBSMN1; SMN2LMNA
P-Xylene SCHEMBL10412500 0.85 ALDH1A1 (0.73) ALDH1A1TSHRTHRBSMN1; SMN2LMNA
O-Xylene SCHEMBL3225611 0.85 ALDH1A1 (0.64) ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10
O-Xylene SCHEMBL7068335 0.83 ALDH1A1 (0.55) ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10
O-Xylene SCHEMBL27964793 0.83 ALDH1A1 (0.61) ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10
Ethyl Acetate SCHEMBL7043012 0.82 ALDH1A1 (0.91) ALDH1A1TSHRTHRBSMN1; SMN2LMNA
SCHEMBL8518918 0.82 ALDH1A1 (1.00) ALDH1A1TSHRTHRBSMN1; SMN2LMNA
SCHEMBL24056 0.82
Acetic Acid Phenyl Ester SCHEMBL7717862 0.81 ALDH1A1 (0.61) ALDH1A1TSHRTHRBSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0184302-B1 ROOM TEMPERATURE-CURING COATING COMPOSITIONS COMPRISING A CONDENSATION POLYMER HAVING BACKBONE ACTIVATED UNSATURATION AND A COMPOUND CARRYING THREE OR MORE PRIMARY AMINO GROUPS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-08-26 EP disclosed
US-4885232-A High temperature post exposure baking treatment for positive photoresist compositions HOECHST CELANESE CORPORATION (US) 1989-12-05 US disclosed
US-4730033-A CURABLE, UNSATURATED POLYESTER, PRIMARY POLYAMINE, LATENCY IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-03-08 US disclosed
EP-0184302-A2 Room temperature-curing coating compositions comprising a condensation polymer having backbone activated unsaturation and a compound carrying three or more primary amino groups IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-06-11 EP disclosed