Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.58 |
| ▸ | AHCY | P23526 | 6/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.56 |
| ▸ | PI4KA | P42356 | 3/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.56 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12157236 | 0.89 | AHCY (0.66) | ADORA2AAHCYADORA3ADORA1ADORA2B | |
| SCHEMBL9687054 | 0.89 | AHCY (0.66) | ADORA2AAHCYADORA3ADORA1ADORA2B | |
| SCHEMBL12173989 | 0.89 | AHCY (0.66) | ADORA2AAHCYADORA3ADORA1ADORA2B | |
| SCHEMBL9308490 | 0.84 | AHCY (0.70) | ADORA2AAHCYADORA3ADORA1ADORA2B | |
| SCHEMBL12858753 | 0.81 | ADORA2A (0.64) | ADORA2AAHCYADORA3ADORA1ADORA2B | |
| SCHEMBL4894825 | 0.81 | ADORA2A (0.64) | ADORA2AAHCYADORA3ADORA1ADORA2B | |
| SCHEMBL9470633 | 0.81 | ADORA2A (0.71) | ADORA2AAHCYADORA3ADORA1ADORA2B | |
| SCHEMBL26230966 | 0.81 | AHCY (0.64) | ADORA2AAHCYADORA3ADORA1ADORA2B | |
| SCHEMBL9687427 | 0.78 | ENPP1 (0.48) | ADORA2AAHCYADORA3ADORA1ADORA2B | |
| SCHEMBL12149495 | 0.78 | AHCY (0.86) | ADORA2AAHCYADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155112-A | Antiviral agents; Herpes virus | GLAXO GROUP LIMITED (GB) | 1992-10-13 | — | — | US | disclosed |
| EP-0430518-A2 | Cyclopentane derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-05 | — | — | EP | disclosed |