Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686096 | 0.85 | MAPT (0.75) | MAPTALDH1A1ADRB2MEN1KMT2A | |
| SCHEMBL109941 | 0.84 | MAPT (0.58) | MAPTGLAALDH1A1ADRB2MEN1 | |
| SCHEMBL111665 | 0.84 | MAPT (0.54) | MAPTGLAALDH1A1ADRB2MEN1 | |
| SCHEMBL30100539 | 0.84 | MAPT (0.54) | MAPTGLAALDH1A1ADRB2MEN1 | |
| SCHEMBL8349564 | 0.82 | MAPT (0.55) | MAPTGLAALDH1A1ADRB2MEN1 | |
| SCHEMBL9807546 | 0.81 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9686092 | 0.77 | MAPT (0.49) | MAPTALDH1A1ADRB2MEN1KMT2A | |
| SCHEMBL10758961 | 0.76 | MAPT (0.54) | MAPTGLAALDH1A1ADRB2MEN1 | |
| SCHEMBL10617199 | 0.76 | MAPT (0.48) | MAPTGLAALDH1A1ADRB2MEN1 | |
| SCHEMBL10485638 | 0.76 | ATM (0.45) | MAPTGLAALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5163970-A | NITRO-P-PHENYLENEDIAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND COLORING AGENTS CONTAINING THESE FOR USE ON KERATIN FIBRES | HANS SCHWARZKOPF GMBH (DE) | 1992-11-17 | — | — | US | disclosed |
| US-5067967-A | Nitro dyes for oxidation color dyes | 501 HANS SCHWARZKOPF GMBH (DE) | 1991-11-26 | — | — | US | disclosed |