Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100539 | 1.00 | MAPT (0.54) | MAPTGLAALDH1A1CYP3A4ADRB2 | |
| SCHEMBL1136820 | 0.88 | MAPT (0.48) | MAPTGLAALDH1A1MEN1KMT2A | |
| SCHEMBL14395463 | 0.86 | MAPT (0.56) | MAPTALDH1A1CYP3A4ADRB2MEN1 | |
| SCHEMBL10716987 | 0.85 | MAPT (0.48) | MAPTGLAALDH1A1MEN1KMT2A | |
| SCHEMBL10758961 | 0.84 | MAPT (0.54) | MAPTGLAALDH1A1CYP3A4ADRB2 | |
| SCHEMBL9686988 | 0.84 | MAPT (0.54) | MAPTGLAALDH1A1CYP3A4ADRB2 | |
| SCHEMBL109941 | 0.84 | MAPT (0.58) | MAPTGLAALDH1A1CYP3A4ADRB2 | |
| SCHEMBL8349564 | 0.82 | MAPT (0.55) | MAPTGLAALDH1A1ADRB2MEN1 | |
| SCHEMBL10756290 | 0.82 | MAPT (0.48) | MAPTGLAALDH1A1CYP3A4MEN1 | |
| SCHEMBL23909 | 0.81 | MAPT (0.51) | MAPTALDH1A1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1060 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12383478-B2 | Cosmetic product for dyeing keratin fibers | KAO CORPORATION (JP) | 2025-08-12 | — | — | US | claimed |
| US-12364660-B2 | Granulated hair dye composition | WELLA GERMANY GMBH (DE) | 2025-07-22 | — | — | US | claimed |
| EP-3873407-B1 | TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING | HENKEL AG & CO KGAA (DE) | 2025-04-09 | — | — | EP | claimed |
| US-20240423887-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | KAO CORPORATION (JP) | 2024-12-26 | — | — | US | claimed |
| WO-2024246126-A1 | DYEING PRODUCT FOR KERATIN FIBERS COMPRISING AMMONIUM SALTS | KAO CORPORATION (JP) | 2024-12-05 | — | — | WO | claimed |
| EP-4247323-B1 | GRANULATED HAIR DYE COMPOSITION | WELLA GERMANY GMBH (DE) | 2024-09-04 | — | — | EP | claimed |
| EP-4408376-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | Kao Corporation (JP) | 2024-08-07 | — | — | EP | claimed |
| US-20240207158-A1 | DYEING COMPOSITION COMPRISING DIRECT DYES | KAO CORPORATION (JP) | 2024-06-27 | — | — | US | claimed |
| US-20240197587-A1 | COSMETIC PRODUCT FOR DYEING KERATIN FIBERS | KAO CORPORATION (JP) | 2024-06-20 | — | — | US | claimed |
| EP-4329710-A1 | COSMETIC PRODUCT FOR DYEING KERATIN FIBERS | Kao Corporation (JP) | 2024-03-06 | — | — | EP | claimed |
| US-4950302-A | Process for the production of 2,5-diamino-6-nitro-pyridine derivatives, their use in hair dye compositions and new 2,5-diamino-6-nitropyridine derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1990-08-21 | — | — | US | claimed |
| US-4921504-A | 4-(N-ethyl-N-2-hydroxyethyl)-amino-1-(2 hydroxyethyl)-amino-2-nitrobenzene and compositions for dyeing hair containing the same | WELLA AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | claimed |
| EP-0184061-B1 | 4-(N-ETHYL,N-2'-HYDROXYETHYL)-AMINO-1-(2\"-HYDROXYETHYL)-AMINO-2-NITROBENZENE AND HAIR DYEING AGENTS | Wella Aktiengesellschaft (DE) | 1988-12-14 | — | — | EP | claimed |
| WO-1988008696-A1 | USE OF 2,6 DINITRO-ANILINE DERIVATIVES IN HAIR TINTING AGENTS AND NEW DERIVATIVES OF 2,6 DINITRO-ANILINE | WELLA AKTIENGESELLSCHAFT (DE) | 1988-11-17 | — | — | WO | claimed |
| EP-0289782-A1 | Use of 2,6-dinitroanilin derivatives in hair dyeing compositions and new 2,6-dinitroanilin derivatives | Wella Aktiengesellschaft (DE) | 1988-11-09 | — | — | EP | claimed |
| EP-0226973-A2 | 4-Bis(2'-hydroxyethyl)amino-1-(3'-hydroxypropyl)amino-2-nitro-benzene, process for its preparation and means for dyeing hair | Wella Aktiengesellschaft (DE) | 1987-07-01 | — | — | EP | claimed |
| EP-0132568-B1 | DERIVATIVES OF 1,4-DIAMINO-5-CHLORO-2-NITROBENZENE, PROCESS FOR THEIR PRODUCTION AND AGENTS FOR DYEING HAIR | Wella Aktiengesellschaft (DE) | 1987-01-28 | — | — | EP | claimed |
| EP-0184061-A1 | 4-(N-ethyl,N-2'-hydroxyethyl)-amino-1-(2\"-hydroxyethyl)-amino-2-nitrobenzene and hair dyeing agents | Wella Aktiengesellschaft (DE) | 1986-06-11 | — | — | EP | claimed |
| EP-0182330-A2 | Use of 2-nitroaniline derivatives as hair dyeing agents, and 2-nitroaniline derivatives | Wella Aktiengesellschaft (DE) | 1986-05-28 | — | — | EP | claimed |
| EP-0132568-A1 | Derivatives of 1,4-diamino-5-chloro-2-nitrobenzene, process for their production and agents for dyeing hair | Wella Aktiengesellschaft (DE) | 1985-02-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12383478-B2 | Cosmetic product for dyeing keratin fibers | KRT18, H1-2, H1-0 | MAPT 662/4885GLA 265/4885ALDH1A1 494/4885 |
| US-20240423887-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | KRT18, COL14A1, COL1A1 | MAPT 496/4885GLA 56/4885ALDH1A1 2007/4885 |
| US-20240197587-A1 | COSMETIC PRODUCT FOR DYEING KERATIN FIBERS | KRT18, H1-2, H1-0 | MAPT 662/4885GLA 265/4885ALDH1A1 494/4885 |
| US-20240207158-A1 | DYEING COMPOSITION COMPRISING DIRECT DYES | KRT18, IK, H1-3 | MAPT 1196/4885GLA 808/4885ALDH1A1 685/4885 |
| US-12364660-B2 | Granulated hair dye composition | SHH, CUTA, DSG1 | MAPT 654/4885GLA 72/4885ALDH1A1 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.