Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685959 | 0.86 | SMN1; SMN2 (0.48) | KMT2ALMNAALDH1A1GAAMEN1 | |
| SCHEMBL28026121 | 0.80 | KMT2A (0.55) | KMT2ALMNAALDH1A1MEN1PTGS1 | |
| SCHEMBL5836723 | 0.80 | KMT2A (0.55) | KMT2ALMNAALDH1A1MEN1PTGS1 | |
| SCHEMBL10982403 | 0.78 | KMT2A (0.53) | KMT2ALMNAALDH1A1KDM4EGAA | |
| SCHEMBL22262945 | 0.78 | KMT2A (0.68) | KMT2ALMNAALDH1A1KDM4EGAA | |
| SCHEMBL16870979 | 0.78 | KMT2A (0.53) | KMT2ALMNAALDH1A1MEN1PTGS1 | |
| SCHEMBL5835956 | 0.77 | KMT2A (0.51) | KMT2ALMNAALDH1A1MEN1PTGS1 | |
| SCHEMBL5835964 | 0.76 | KMT2A (0.50) | KMT2ALMNAALDH1A1MEN1PTGS1 | |
| SCHEMBL7043903 | 0.73 | KMT2A (0.58) | KMT2ALMNAALDH1A1MEN1PTGS1 | |
| SCHEMBL8686326 | 0.73 | KMT2A (0.58) | KMT2ALMNAALDH1A1GAAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147952-A | PROCESS FOR PRODUCING MACROMOLECULAR MONOMER | TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-09-15 | — | — | US | disclosed |