Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685691 | 0.78 | KMT2A (0.44) | LMNAGSRALDH1A1NPC1KMT2A | |
| SCHEMBL10393559 | 0.78 | LMNA (0.47) | LMNAGSRALDH1A1NPC1KMT2A | |
| SCHEMBL11817354 | 0.78 | NPC1 (0.41) | LMNAGSRALDH1A1NPC1KMT2A | |
| SCHEMBL11108771 | 0.73 | GSR (0.40) | LMNAGSRALDH1A1NPC1KMT2A | |
| SCHEMBL3388678 | 0.72 | LMNA (0.46) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1507251 | 0.72 | LMNA (0.46) | LMNAALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL2319965 | 0.71 | LMNA (0.43) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL19292352 | 0.70 | LMNA (0.48) | LMNAALDH1A1MAPTCYP2C19 | |
| SCHEMBL266714 | 0.70 | LMNA (0.43) | LMNAGSRALDH1A1NPC1KMT2A | |
| SCHEMBL7137546 | 0.70 | LMNA (0.38) | LMNAGSRALDH1A1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147952-A | PROCESS FOR PRODUCING MACROMOLECULAR MONOMER | TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-09-15 | — | — | US | disclosed |