SCHEMBL9687072

SCHEMBL9687072

O=C1COc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc2N1Cc1cnccn1

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 1/20 0.35
BRD4 O60885 1/20 0.35
HDAC6 Q9UBN7 2/20 0.35
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9685904 0.86 BRD4 (0.49) BRD4
SCHEMBL9686487 0.81 CYP1B1 (0.36) CYP1B1
SCHEMBL10376307 0.80 GRM7 (0.40)
SCHEMBL10374243 0.78 GRM7 (0.37)
SCHEMBL10338402 0.77 CHRM1 (0.42)
Flumioxazin SCHEMBL39699 0.76 GRM1 (0.37)
SCHEMBL10531135 0.75 GRM7 (0.40)
SCHEMBL9686505 0.74 BRD4 (0.45) BRD4
SCHEMBL9687801 0.74 BRD4 (0.57) BRD4
SCHEMBL9685821 0.73 BRD4 (0.44) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0296416-B1 BENZO-ANELLATED CYCLIC COMPOUNDS NIHON BAYER AGROCHEM K.K. (JP) 1992-07-29 EP disclosed
US-5077401-A Herbicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1991-12-31 US disclosed
US-4902335-A Benzo-fused cyclic compounds NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1990-02-20 US disclosed
EP-0296416-A1 Benzo-anellated cyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1988-12-28 EP disclosed