Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634950 | 0.90 | SLC6A9 (0.53) | SLC6A9TP53MAPTMEN1KMT2A | |
| Oxalic Acid SCHEMBL9635944 | 0.89 | SLC6A9 (0.54) | SLC6A9TP53MAPTCHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9635939 | 0.89 | SLC6A9 (0.54) | SLC6A9TP53MAPTCHRM5CHRM1 | |
| SCHEMBL9636292 | 0.88 | SLC6A9 (0.55) | SLC6A9TP53MAPTCHRM5CHRM1 | |
| SCHEMBL9636377 | 0.87 | SLC6A9 (0.55) | SLC6A9TP53MAPTCHRM5CHRM1 | |
| SCHEMBL9687136 | 0.87 | SLC6A9 (0.55) | SLC6A9TP53MAPTCHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9634559 | 0.87 | SLC6A9 (0.59) | SLC6A9TP53MAPTCHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9634553 | 0.87 | SLC6A9 (0.59) | SLC6A9TP53MAPTCHRM5CHRM1 | |
| SCHEMBL9636222 | 0.87 | SLC6A9 (0.55) | SLC6A9TP53MAPTCHRM5CHRM1 | |
| Oxalic Acid SCHEMBL9635891 | 0.86 | SLC6A9 (0.52) | SLC6A9TP53MAPTCHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307014-B1 | ANTI-ALLERGIC 2-(HETEROCYCLYL ALKYL) IMIDAZO PYRIDINES AND 2-(HETEROCYCLYL ALKYL) PURINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-09 | — | — | EP | disclosed |
| EP-0307014-A1 | Anti-allergic 2-(heterocyclyl alkyl) imidazo pyridines and 2-(heterocyclyl alkyl) purines | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-03-15 | — | — | EP | disclosed |