Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.57 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3754419 | 0.87 | CYP2A6 (0.68) | MKNK1MKNK2CYP2A6HSD17B1HSD17B2 | |
| SCHEMBL31174412 | 0.87 | CYP2A6 (0.68) | MKNK1MKNK2CYP2A6HSD17B1HSD17B2 | |
| SCHEMBL2212520 | 0.83 | — | — | |
| SCHEMBL1422493 | 0.82 | MKNK1 (0.59) | MKNK1MKNK2CYP2A6HSD17B1HSD17B2 | |
| SCHEMBL12497850 | 0.82 | MKNK1 (0.59) | MKNK1MKNK2CYP2A6HSD17B1HSD17B2 | |
| SCHEMBL1422182 | 0.82 | HSD17B1 (0.67) | MKNK1MKNK2CYP2A6HSD17B1HSD17B2 | |
| SCHEMBL5052703 | 0.80 | MKNK1 (0.57) | MKNK1MKNK2CYP2A6HSD17B1HSD17B2 | |
| SCHEMBL969720 | 0.80 | MKNK1 (0.57) | MKNK1MKNK2CYP2A6HSD17B1HSD17B2 | |
| SCHEMBL17742850 | 0.80 | MKNK1 (0.57) | MKNK1MKNK2CYP2A6HSD17B1HSD17B2 | |
| SCHEMBL13575396 | 0.80 | MKNK1 (0.57) | MKNK1MKNK2CYP2A6HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |