Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 6/20 | 0.32 |
| ▸ | ATP4B | P51164 | 6/20 | 0.32 |
| ▸ | ATP1A1 | P05023 | 4/20 | 0.32 |
| ▸ | ATP1B1 | P05026 | 4/20 | 0.32 |
| ▸ | ATP1A3 | P13637 | 4/20 | 0.32 |
| ▸ | ATP1B2 | P14415 | 4/20 | 0.32 |
| ▸ | ATP1A2 | P50993 | 4/20 | 0.32 |
| ▸ | ATP1B3 | P54709 | 4/20 | 0.32 |
| ▸ | FXYD2 | P54710 | 4/20 | 0.32 |
| ▸ | ATP1A4 | Q13733 | 4/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | CBFB | Q13951 | 2/20 | 0.31 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456203 | 0.90 | TRPV1 (0.45) | TRPV1ATP4AATP4BATP1A1ATP1B1 | |
| SCHEMBL10751918 | 0.89 | TRPV1 (0.45) | TRPV1ATP4AATP4BATP1A1ATP1B1 | |
| SCHEMBL9676777 | 0.84 | NPSR1 (0.45) | TRPV1LMNAPOLBATP4AATP4B | |
| SCHEMBL9531062 | 0.83 | USP30 (0.36) | TRPV1LMNAPOLBSCN10ACBFB | |
| SCHEMBL2108293 | 0.83 | RUNX1 (0.43) | TRPV1LMNASCN10ACBFBRUNX1 | |
| SCHEMBL482378 | 0.80 | NPC1 (0.41) | LMNAATP4AATP4BATP1A1ATP1B1 | |
| SCHEMBL9456207 | 0.79 | TRPV1 (0.54) | TRPV1ATP4AATP4BATP1A1ATP1B1 | |
| SCHEMBL8304476 | 0.73 | CACNA1B (0.40) | LMNAATP4AATP4BATP1A1ATP1B1 | |
| SCHEMBL9674998 | 0.73 | NPSR1 (0.49) | TRPV1LMNAPOLBATP4AATP4B | |
| SCHEMBL10623969 | 0.73 | KDM4E (0.50) | TRPV1LMNAPOLBATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201575-B1 | NEW PICOLINE DERIVATIVES, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1992-08-12 | — | — | EP | disclosed |
| US-4686230-A | Picoline derivative useful as gastric acid secretion inhibitors | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1987-08-11 | — | — | US | disclosed |
| EP-0201575-A1 | NEW PICOLINE DERIVATIVES, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM. | BYK GULDEN LOMBERG CHEM FAB (DE) | 1986-11-20 | — | — | EP | disclosed |
| WO-1986002646-A1 | NEW PICOLINE DERIVATIVES, PREPARATION PROCESS THEREOF, UTILIZATION THEREOF AND DRUGS CONTAINING THEM | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT M (DE) | 1986-05-09 | — | — | WO | disclosed |