Sugi Predict

Sugi Predict / Compounds / SCHEMBL482378

SCHEMBL482378

SCHEMBL482378

FC(F)Oc1ccc2[nH]c(S)nc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 3/20 0.41
▸ RAB9A P51151 3/20 0.41
▸ PKM P14618 1/20 0.41
▸ CYP3A4 P08684 2/20 0.38
▸ CYP2C9 P11712 2/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ CYP2E1 P05181 1/20 0.38
▸ CYP2C8 P10632 1/20 0.38
▸ CYP2D6 P10635 1/20 0.38
▸ CYP2B6 P20813 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ LMNA P02545 3/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ TP53 P04637 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ ENPP1 P22413 1/20 0.35
▸ KDM4E B2RXH2 3/20 0.35
▸ ATP4A P20648 5/20 0.35
▸ ATP4B P51164 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2108226 0.87 CYP3A4 (0.49) NPC1RAB9APKMCYP3A4CYP2C9
SCHEMBL9305942 0.84 PDE3B (0.46) NPC1RAB9ACYP3A4CYP2C9CYP1A2
SCHEMBL9456203 0.83 TRPV1 (0.45) KMT2AKDM4EATP4AATP4BATP1A1
SCHEMBL12957900 0.81 PDE2A (0.43) NPC1RAB9APKMCYP3A4CYP2C9
SCHEMBL2108293 0.81 RUNX1 (0.43) NPC1RAB9APKMCYP3A4CYP2C9
SCHEMBL9687343 0.80 TRPV1 (0.38) LMNAATP4AATP4BATP1A1ATP1B1
SCHEMBL9531062 0.78 USP30 (0.36) NPC1RAB9APKMCYP3A4CYP2C9
SCHEMBL916531 0.78 ALDH1A1 (0.48) NPC1RAB9APKMCYP3A4CYP2C9
SCHEMBL14496038 0.77 CYP1A2 (0.46) NPC1RAB9APKMCYP3A4CYP2C9
SCHEMBL9148452 0.77 ALDH1A1 (0.47) NPC1RAB9APKMCYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798220-A Preparation method of digestive drug intermediate 山东罗欣药业集团恒欣药业有限公司 2025-04-11 — — CN claimed
CN-119661811-A Latent accelerator based on anhydride-tertiary amine dynamic ion pair, preparation method and application thereof 江南大学 2025-03-21 — — CN claimed
CN-119078337-A Production process of bio-based waterproof and moisture permeable glove lining material 伊帆特纺织品(上海)有限公司 2024-12-06 — — CN claimed
CN-119020880-A Preparation method of self-pumping bionic fiber membrane and application of self-pumping bionic fiber membrane in antibacterial dressing 吉林省科百医疗器材有限公司 2024-11-26 — — CN claimed
CN-116332438-B Treatment method of landfill leachate membrane concentrate 湖南环宏环保科技有限公司 2023-07-21 — — CN claimed
CN-116332438-A Treatment method of landfill leachate membrane concentrate 湖南环宏环保科技有限公司 2023-06-27 — — CN claimed
CN-116322094-A Perovskite solar cell passivated by sulfur-containing passivating agent 陕西师范大学 2023-06-23 — — CN claimed
CN-114621188-A Preparation method of pantoprazole 南京科技职业学院 2022-06-14 — — CN claimed
CN-111117136-B Cable material 温州大学 2022-06-07 — — CN claimed
CN-108285456-B 4-sulfur substituted podophyllotoxin derivative and preparation method and application thereof 汤亚杰 2022-02-08 — — CN claimed
CN-102020637-A Preparation method of 5-difluoromethoxy-2-[[(3,4-dimethoxy-2-pyridyl)methyl]thio]-1H-benzimidazole ZHEJIANG HUAYI PHARMACEUTICAL CO LTD 2011-04-20 — — CN claimed
US-20100210847-A1 PROCESS FOR THE PREPARATION OF PANTOPRAZOLE SODIUM AND PANTOPRAZOLE SODIUM SESQUIHYDRATE RANBAXY LABORATORIES LIMITED (IN) 2010-08-19 — — US claimed
EP-2181106-A1 PROCESS FOR THE PREPARATION OP PANTOPRAZOLE SODIUM AND PANTOPRAZOLE SODIUM SESQUIHYDRATE Ranbaxy Laboratories Limited (IN) 2010-05-05 — — EP claimed
US-20100016605-A1 Process CIPLA LIMITED (IN) 2010-01-21 — — US claimed
WO-2009010937-A1 PROCESS FOR THE PREPARATION OP PANTOPRAZOLE SODIUM AND PANTOPRAZOLE SODIUM SESQUIHYDRATE RANBAXY LABORATORIES LIMITED (IN) 2009-01-22 — — WO claimed
WO-2008001392-A2 AN IMPROVED PROCESS FOR THE PREPARATION OF PANTOPRAZOLE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS MSN LABORATORIES LIMITED (IN) 2008-01-03 — — WO claimed
WO-2007086077-A2 A NOVEL ONE POT PROCESS FOR PREPARATION OF PANTOPRAZOLE SODIUM SESQUIHYDRATE UNICHEM LABORATORIES LIMITED (IN) 2007-08-02 — — WO claimed
WO-2006064249-A2 PROCESS FOR THE PREPARATION OF PANTOPRAZOLE SODIUM CIPLA LIMITED (IN) 2006-06-22 — — WO claimed
WO-2004092142-A1 AN IMPROVED PROCESS FOR MANUFACTURE OF SUBSTITUTED BENZIMIDAZOLES IPCA LABORATORIES LIMITED (IN) 2004-10-28 — — WO claimed
EP-0166287-B1 DIALKOXYRIDINES, PROCESS FOR THEIR PREPARATION, THEIR APPLICATION AND MEDICAMENTS CONTAINING THEM Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1989-08-23 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210847-A1 PROCESS FOR THE PREPARATION OF PANTOPRAZOLE SODIUM AND PANTOPRAZOLE SODIUM SESQUIHYDRATE VKORC1, PANK3, NISCH NPC1 1519/4885RAB9A 721/4885PKM 1256/4885
US-20100016605-A1 Process MPST, HPD, POR NPC1 2579/4885RAB9A 1892/4885PKM 1365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.