Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Isobutyramide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutyramide SCHEMBL10569453 | 0.97 | TSHR (0.38) | — | |
| Isobutyramide SCHEMBL7705026 | 0.89 | TDP1 (0.53) | — | |
| Isobutyramide SCHEMBL2043053 | 0.87 | LMNA (0.35) | — | |
| Isobutyramide SCHEMBL5469885 | 0.87 | CA1 (0.44) | — | |
| Isobutyramide SCHEMBL7033603 | 0.87 | LMNA (0.35) | — | |
| Isobutyramide SCHEMBL3323 | 0.86 | — | — | |
| Isobutyramide SCHEMBL11109750 | 0.86 | LMNA (0.46) | — | |
| Isobutyramide SCHEMBL10808105 | 0.84 | CA1 (0.37) | — | |
| Isobutyramide SCHEMBL18321221 | 0.82 | — | — | |
| Isobutyramide SCHEMBL22719097 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195197-B | Magnetic porous carbon compound and preparation method and application thereof | 浙江工业大学 | 2024-03-26 | — | — | CN | claimed |
| US-9669048-B2 | Stable pharmaceutical composition of 5-aza-2′-deoxycitidine | FRESENIUS KABI ONCOLOGY LIMITED (IN) | 2017-06-06 | — | — | US | claimed |
| CN-104611773-B | A kind of decentralized casing spinneret arranged side by side and application thereof | 上海理工大学 | 2017-01-04 | — | — | CN | claimed |
| US-11072741-B2 | Optically anisotropic layer, method for producing the optically anisotropic layer, a laminate, polarizing plate, display device, liquid crystal compound, method for producing the liquid crystal compound, and carboxylic acid compound | FUJIFILM CORPORATION (JP) | 2021-07-27 | — | — | US | disclosed |
| CN-109879890-A | A method of preparing thiophene oxime azoles cephalo | 陕西修风生物科技有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109879889-A | A kind of cefuroxime axetil tablet composition and preparation method thereof | 陕西修风生物科技有限公司 | 2019-06-14 | — | — | CN | disclosed |
| US-20180346814-A1 | OPTICALLY ANISOTROPIC LAYER, METHOD FOR PRODUCING THE OPTICALLY ANISOTROPIC LAYER, A LAMINATE, POLARIZING PLATE, DISPLAY DEVICE, LIQUID CRYSTAL COMPOUND, METHOD FOR PRODUCING THE LIQUID CRYSTAL COMPOUND, AND CARBOXYLIC ACID COMPOUND | FUJIFILM CORPORATION (JP) | 2018-12-06 | — | — | US | disclosed |
| US-10059877-B2 | Optically anisotropic layer, method for producing the optically anisotropic layer, a laminate, polarizing plate, display device, liquid crystal compound, method for producing the liquid crystal compound, and carboxylic acid compound | FUJIFILM CORPORATION (JP) | 2018-08-28 | — | — | US | disclosed |
| US-20160108315-A1 | OPTICALLY ANISOTROPIC LAYER, METHOD FOR PRODUCING THE OPTICALLY ANISOTROPIC LAYER, A LAMINATE, POLARIZING PLATE, DISPLAY DEVICE, LIQUID CRYSTAL COMPOUND, METHOD FOR PRODUCING THE LIQUID CRYSTAL COMPOUND, AND CARBOXYLIC ACID COMPOUND | FUJIFILM CORPORATION (JP) | 2016-04-21 | — | — | US | disclosed |
| EP-0270494-B1 | Certain cycloalka- [b]-pyrazolo-[3,4-d]-pyridin-3-one derivatives | CIBA-GEIGY AG (CH) | 1992-08-19 | — | — | EP | disclosed |
| US-4713383-A | ADENOSINE AND BENZODIAZEPINE ANTAGONISTS | CIBA-GEIGY CORPORATION (US) | 1987-12-15 | — | — | US | disclosed |